Born in New York City, Harry Worthman knew early in life that art was to be his career. After graduating from high school, Worthman attended the Art Students League in New York City, studying under such well-known artists as George Bridgman, Dean Cornwell and Frank Vincent Dumond. He also studied at the National Academy of Design and the Cooper Union, both in New York City.
In 1948, Worthman moved to Texas where he finished out his career. Primarily a portrait artist, Harry Worthman produced his finest works in that genre.